Movement Disorders (revue)

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Atypical movement disorders in antiphospholipid syndrome

Identifieur interne : 003576 ( Main/Exploration ); précédent : 003575; suivant : 003577

Atypical movement disorders in antiphospholipid syndrome

Auteurs : Davide Martino [Royaume-Uni, Italie] ; Nee-Kong Chew [Royaume-Uni, Malaisie] ; Pablo Mir [Royaume-Uni, Espagne] ; Mark J. Edwards [Royaume-Uni] ; Niall P. Quinn [Royaume-Uni] ; Kailash P. Bhatia [Royaume-Uni]

Source :

RBID : ISTEX:CE5912ACEC6C9DF3B6B58AEAEAD7EF4CFEE742CD

Descripteurs français

English descriptors

Abstract

Movement disorders have only rarely been reported in association with antiphospholipid syndrome (APS). In such cases, chorea is the most common disorder observed, with occasional reports of hemidystonia, Parkinsonism, and hemiballism. We report here on 3 cases of APS (3 women ages 16, 46, and 56 years) who presented with movement disorders, including tics, tremor, myoclonus, and a corticobasal syndrome, never or rarely reported in association with this disease. Mild executive dysfunction was observed in all 3 patients. We also report the successful treatment of two of these patients with mild oral anticoagulation (INR 2–3). Movement disorders in APS seem more clinically heterogeneous than previously thought. Oral anticoagulation should be considered in the treatment of movement disorders associated with APS. © 2006 Movement Disorder Society

Url:
DOI: 10.1002/mds.20842


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<div type="abstract" xml:lang="en">Movement disorders have only rarely been reported in association with antiphospholipid syndrome (APS). In such cases, chorea is the most common disorder observed, with occasional reports of hemidystonia, Parkinsonism, and hemiballism. We report here on 3 cases of APS (3 women ages 16, 46, and 56 years) who presented with movement disorders, including tics, tremor, myoclonus, and a corticobasal syndrome, never or rarely reported in association with this disease. Mild executive dysfunction was observed in all 3 patients. We also report the successful treatment of two of these patients with mild oral anticoagulation (INR 2–3). Movement disorders in APS seem more clinically heterogeneous than previously thought. Oral anticoagulation should be considered in the treatment of movement disorders associated with APS. © 2006 Movement Disorder Society</div>
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